Government panel recommends stronger regulates about painkiller Vicodin

In a move to stem the epidemic of prescription drug deaths, a federal advisory panel has encouraged tighter controls on the narcotic painkiller very best recognized through the brand title Vicodin. It is actually the nation's most broadly prescribed drug.

By a 19-to-10 vote, an advisory panel for the U.S. Meals and Drug Administration encouraged Friday the agency reclassify hydrocodone, the energetic ingredient in Vicodin, being a Routine II narcotic, putting it inside the exact same category as other extensively abused drugs, like OxyContin and fentanyl.

Should the FDA approves the adjust, individuals could be capable to get fewer hydrocodone capsules at 1 time, and there could be a lot more restrictions on refills. Additionally, pharmacies would need to comply with stricter procedures for managing and storing the drug.

Routine II could be the government's most restrictive category for pharmaceuticals with accepted health care utilizes. Hydrocodone is now listed on Routine III.

The Usa consumes 99% with the hydrocodone made throughout the world, and medical professionals compose additional prescriptions for it than for your main antibiotic and hypertension medicines.

Prescription medicines ?a largely narcotic painkillers this kind of as hydrocodone ?a bring about or contribute to extra deaths than heroin and cocaine mixed. Because of this, drug fatalities have surpassed deaths from motor motor vehicle crashes, extended the major reason for accidental death within this nation.

A Los Angeles Instances examination of three,733 prescription drug-related fatalities in Southern California from 2006 by way of 2011 discovered that hydrocodone was associated with 945 on the deaths, greater than any other prescription medicine.

Medical practitioners have prescribed hydrocodone with handful of restrictions because it was introduced 4 decades ago. As a consequence of the perception that it really is significantly less risky than other narcotic painkillers, it can be extensively prescribed by standard practitioners and dentists.

Nevertheless drug enforcement officials have prolonged complained that hydrocodone was very addictive and broadly abused.

For many years, the FDA resisted tightening the guidelines on its use from concern that performing so would make it extra tough for individuals with respectable ache to receive the drug. The U.S. Drug Enforcement Administration asked the agency to reconsider in light from the drug's widespread availability around the black industry.

Earlier this week, the American Academy of Discomfort Medicine sent the FDA advisory panel a letter saying that though it had some concern that tighter guidelines could curtail genuine prescribing, it didn't oppose moving hydrocodone to Routine II.

Morgan Liscinsky, a spokeswoman for your FDA, mentioned she couldn't say once the agency would act within the recommendation.

In searching for to stem the maximize in fatal drug overdoses, authorities have focused on how addicts and drug dealers acquire prescription narcotics illegally, this kind of as by stealing from pharmacies or relatives' medicine cabinets. Latest content articles within the Occasions, nevertheless, reported that several overdoses stem from medicines prescribed for that deceased by a health care provider.

In just about half in the prescription drug fatalities in 4 Southern California counties, prescription drugs prescribed by doctors brought about or contributed to your death, in accordance with a Instances examination of coroners' records.

Seventy-one physicians, a small fraction of all practicing doctors inside the 4 counties, have been linked having a disproportionate variety of deaths.

In response on the posts, the Healthcare Board of California has appealed towards the public to report cases of extreme prescribing, and legislative leaders, which includes the president of your California Senate, have promised to offer the board extra investigators and higher authority to end reckless prescribing.

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Gucci Mane's 'Spring Breakers' Function Can make Waka Flocka Laugh

'He did that about the very low. I cannot wait to check out it,' Waka tells MTV News of his buddy's purpose from the approaching James Franco flick.

Gucci Mane is extra trap God than educated thespian, but that did not halt the Atlanta rap star from landing a purpose alongside James Franco and Selena Gomez from the approaching "Spring Breakers."

If Gucci's function as Archie took you by surprise, never fret, even his closest partners had been kept inside the dark about his big-screen acting debut.

"Honestly, he did that over the reduced. He knew I was gonna laugh at him," Waka Flocka Flame advised MTV News on Thursday precisely the same day we premiered the flick's wild trailer. "He did that over the minimal. I cannot wait to determine it."

The film which also stars Vanessa Hudgens, Ashley Benson and Rachel Korine centers close to 4 school women who head to some fairly heinous lengths to fund their spring break trip. Just after they get busted, Alien, a drug dealer played by Franco, bails them out only to get them place in operate for him.

In October, Gucc sat down with Electrical power 105's Breakfast Club in New York City and attempted his finest to break down the premise from the film. "It's a white film," he mentioned. "I'm the only black man inside the entire film. It is a white film. It is like a white Pulp Fiction... I am the lousy man. That is what they wished me to perform. I could happen to be the very good man if they desired me to."

The "Wasted" rapper is not the just one who's manufactured a departure from normalcy for your film, his co-star Selena Gomez identified herself in the considerably darker function than she is made use of to taking part in. "Disney was my daily life, and within a way, it truly is all I knew, so the moment that ended, I unquestionably believe it had been fantastic for me to head to an severe like this," she explained. "That's what was so liberating about this. I felt so secure with Harmony , and I felt so risk-free with all the women. I was definitely capable to push myself to locations even I did not know I could go. It had been terrific."

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NFC 2010 playoffs: 49ers bump Green bay packers 45-31

Ever due to the fact coach Jim Harbaugh gave second-year quarterbackColin Kaepernick the commencing nod more than hot-handed Alex Smith, the query has hovered above the 49ers like a cloud.

Did Harbaugh make the ideal determination?

The highly effective and elusive Kaepernick presented a resounding response Saturday evening using a record-setting effectiveness within a 45-31 victory more than the Packers inside a divisional playoff game at Candlestick Park.

On the evening when Kaepernick became Keepernick, the 49ers quarterback torched the Packers with his arm and his feet, rushing for two touchdowns and throwing for two.

He scored on runs of twenty and 56 yards. The 56-yarder was the longest run by a quarterback inside the playoffs, surpassing a 51-yard run through the Titans' Steve McNair in Jan. 2000.

"Guy's taking part in football, guy, he's which makes it come about," 49ers receiver Michael Crabtree explained of Kaepernick. "He's a playmaker."

Kaepernick also shattered Michael Vick's mark of 119 yards rushing -- the past postseason rushing record by a quarterback -- having a game-high 181 yards on 16 carries.

"The offense that we've produces a whole lot of confusion with all the quarterback we now have who can run as rapid as he can," stated tackle Joe Staley, a part of an offense that gained 323 yards around the ground and 579 complete. "He may also throw the ball downfield. We need to move the chains any way we are able to, but it really is terrific to move the ball together with the ground game."

Kaepernick received off to a bumpy start off ¡§C his 2nd pass was intercepted and run back 52 yards to get a touchdown ¡§C but he under no circumstances lost his composure, upstaging Packers quarterback Aaron Rodgers, the NFL's reigning most useful player.

"Anytime your teammates have self confidence in you and so they really feel very good about what you are accomplishing, it tends to make you're feeling like you are executing the correct factors," Kaepernick stated.

The Packers have been outscored 21-0, within the 2nd half and had two turnovers that led to 49ers touchdowns.

"It's rather aggravating," explained Rodgers, who threw for 257 yards with two touchdowns and an interception. "To go out and perform like that's disappointing. We did not do sufficient on offense to aid our defense."

For that 2nd consecutive season, San Francisco has innovative on the NFC championship game in which it is going to encounter the winner of Sunday's game in between the Seahawks and Falcons.

"They competed like maniacs," Harbaugh mentioned of his gamers, "and now we have received an additional week of function."

It had been a large day for that Harbaugh family members, with Jim's older brother, John, coaching the Ravens to a double-overtime win at Denver.

"That was a actual football battle," Jim mentioned of your Ravens' 38-35 victory. "Had an opportunity to view several of it ahead of our game. Really feel good for John and his crew."

The Packers saw their season open and near with losses for the 49ers. They dropped their opener to San Francisco 30-22 at Lambeau Field.

Saturday's rematch featured Rodgers, a 49ers fan in Northern California who wore a Joe Montana T-shirt underneath his pads like a kid, and Kaepernick, who was born in Milwaukee and grew up idolizing Brett Favre.

Crabtree caught two touchdown passes to the 49ers, and Frank Gore and Anthony Dixon just about every ran for the score.

Regardless of it staying his 1st postseason start out, Kaepernick was unflappable, even right after the pick-six interception to start out the game. He came back within the subsequent possession and orchestrated an eight-play, 80-yard drive that ended with his 20-yard keeper to get a
touchdown. That came on third-and-8, and -- as opposed to his longer touchdown run -- was not a planned run for him.

"Man-to-man coverage, they doubled Crab, broke down and I saw a operating lane," the quarterback explained using a shrug.

Place simply just by Packers receiver Greg Jennings: "We lost to a superior crew currently."

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Jaguars hearth Paul Mularkey

The a lot more Jacksonville Jaguars proprietor Shad Khan watched his crew perform, the additional he recognized something:

"We desired a rebuild from your ground up," Khan explained.

So the Jaguars fired coach Mike Mularkey on Thursday soon after just 1 season, the worst in franchise background. The move came ten days right after Khan fired basic manager Gene Smith.

Khan also introduced new GM David Caldwell on Thursday, and by parting methods with Mularkey, gave him a clean slate heading into 2013.

"I've constantly been a a part of a winner," explained Caldwell, who signed a five-year deal. "I've under no circumstances been a a part of a losing crew."

Mularkey gets the eighth NFL coach fired because the common season ended. Two of these teams have considering the fact that employed new coaches, with Andy Reid, who was fired through the Eagles, taking above the Chiefs and Doug Marrone joining the Expenses.

Between candidates to the Jaguars coaching occupation are anticipated to get 49ers offensive coordinator Greg Roman, Rams offensive coordinator Brian Schottenheimer and Falcons special-teams coach Keith Armstrong, league sources informed ESPN.

Roman and Caldwell have been teammates and roommates while in the 1990s even though attending John Carroll University.

"I consider Greg is often a heck of the coach," Caldwell mentioned.

The Jaguars currently have requested permission through the Rams to interview Schottenheimer, in accordance with a league supply. Schottenheimer interviewed to the Jaguars' work final year.

Mularkey, who went 2-14 this season, became the eighth head coach fired because the finish in the frequent season. He looked like he might be a single and performed when Khan parted methods with Smith final week and gave Mularkey's assistants permission to look for other jobs. Despite the fact that Khan eventually employed Mularkey, Smith directed the coaching search final January that commenced and ended using the former Atlanta Falcons offensive coordinator.

"I felt like we wanted a fresh get started right here," Caldwell explained. "Coming in right here as being a first-time standard manager, I am trying to find a co-builder of our group. When I talked to Shad with regards to a culture transform along the football side, I felt like it had been a lot more of that. I felt like it had been an environment of adjust. I felt like that to complete that, you have to get a fresh start off across the board."

Mularkey's short tenure -- he did not even final a year -- was filled with faults. His most significant a single may perhaps are his loyalty to Smith, who assembled a roster that lacked talent on the two sides in the ball.

Mularkey likely caught with Smith's franchise quarterback, Blaine Gabbert, longer than he should really have. And also the coach's insistence the group was closer than outsiders imagined and his powerful stance that he had the roster to turn issues all around became comical since the losses mounted. The Jaguars lost eight video games by at the very least 16 factors, a staggering amount of lopsided losses inside a parity-filled league.

Mularkey would have already been superior served had he mentioned publicly what he voiced privately: The Jaguars did not have sufficient playmakers or perhaps a starting-caliber quarterback.

As a substitute, he hardly ever conceded that Jacksonville was a rebuilding venture that required time.

Now it's -- and Khan produced that clear Thursday.

"A year ago, when I came right here, the organizational judgment was we have been a fairly excellent crew, only a handful of gamers along with a draft far from seriously competing for any playoff spot," Khan explained. "As the year progressed, it had been fairly clear that was not the situation, and we would want a fresh start off as well as a rebuild in the ground up."

Mularkey signed a three-year contract on Jan. 11, 2012, acquiring a 2nd opportunity to become a head coach 6 many years just after resigning using the Buffalo Expenses.

His return was shaky through the get started.

His most effective player, operating back Maurice Jones-Drew, skipped offseason routines at the same time as education camp as well as the preseason within a contract dispute. His to start with draft select, receiver Justin Blackmon, was arrested and charged with aggravated DUI in June. And his group was riddled with injuries, like important ones to linebacker Daryl Smith and Jones-Drew.

Even points Mularkey had management in excess of went awry.

He needed to backtrack following saying Chad Henne would compete with Gabbert to the starting up work in March. He designed a stir by threatening to fine gamers as much as $10,000 for discussing injuries. He at first played rookie receiver Kevin Elliott in excess of Cecil Shorts III early on. And he actually irked some gamers with hard, padded practices late inside a lost season.

Throw while in the way he handled injuries to receiver Laurent Robinson (4 concussions well before happening IR) and Jones-Drew (admittedly need to have had foot surgical treatment sooner), and there have been good reasons to doubt no matter whether Mularkey was lower out to get a head coach. Dating back to his last season in Buffalo, Mularkey has lost twenty of his final 23 video games.

Caldwell and Mularkey spent 4 many years with each other in Atlanta, finding to learn one another nicely adequate that Caldwell did not will need a sit down with Mularkey immediately after he got the GM occupation Tuesday.

"It was difficult," Caldwell mentioned. "I possess a ton of respect for Mike. ... It can be by no means effortless and that is likely the worst a part of the company."

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MTV's 'Washington Heights' Best: The particular Solid around the Heights' Rebirth and also Revolutionizing Fact Television

From the network that gave us The Hills and Jersey Shore comes a display in contrast to any of its predecessors. Confident, MTV's Washington Heights follows a equivalent reality Television formula ¡§C documenting 6 mates who have been born and raised in Manhattan's northern-most neighborhood ¡§C but in contrast to Lauren Conrad and Co., J.P. and his mates have heart, plus they dress in it nearly as proudly because they dress in their adore on the Heights.

For that cast of Washington Heights, this is not only a area wherever they reside: it really is a culture, it truly is a way of life, and most importantly, it really is residence. J.P. and his buddies ¡§C Reyna, Frankie, Ludwin, Fred, Rico, Jimmy and Taylor ¡§C grew up from the Heights, only a handful of blocks far from each other. An aspiring rapper, J.P. (who goes through the moniker Audubon) conceived the concept to the docu-series 3 year before production.

"New York City has under no circumstances been portrayed this genuine or this really hard," J.P. informed Celebuzz. "And it truly is not HBO. It can be not a film. There have been exhibits that glamorized the intercourse of your city, the garments along with the clubs, but our demonstrate is about culture. That is what can make it fully diverse. There is under no circumstances been this considerably culture on Television well before."

"The display has not taken off, and I truly feel like we have presently created background just by becoming an all-Hispanic cast on tv," he extra. "And 3 from the 4 creators are Hispanic. I am proud of us by now!"

Having said that, the docu-series does fall victim to a number of reality display tropes. While in the to start with episode, and explosive fright in between Reyna and Eliza fractures the group to get a bulk with the season.

"It's like when you are strolling down the street and there is constantly slightly Chihuahua barking on the Pit-bull," Rico joked of Reyna's feisty frame of mind.

The 2 have still to resolve their variations. ("Sometimes, she has that encounter and I just desire to slap her," mentioned Reyna.) But based on the cast, that is not indicative with the complete series.

"That's the 1st and final time a large battle occurred in between us," explained J.P. "That messed up every thing. I was not speaking to Jimmy for, like, 4 months right after that battle. That battle sucked. I dislike reliving that second, but points happen?- I am glad we get that from the way in which within the initial episode so from the finish in the season, men and women can have forgotten about this. Which is not what the display is about.

As an alternative, the series aims to highlight the Heights the way in which J.P. and his mates see it: like a cultual Mecca.

"It's been an extended time coming," stated Frankie, a functionality poet. "People are often inspired by folks from comparable walks of daily life, so I cannot wait for people today to view what inspires us simply because hopefully, it is going to inspire them."

"We encourage one another to complete superior," extra Fred.

In advance of joining the cast, Fred, now an aspiring style designer, was functioning in property ¡§C and admittedly, he was miserable.

"I was not chasing my dreams, I was chasing what my mothers and fathers needed me to complete," he mentioned. "And when I'd hang out with J.P. as well as Ludwin, who was like, 'All I would like to do is paint,' I recognized that I ought to be going soon after my dreams the identical way they had been going following theirs."

"I just could not see myself inside a retail keep or at a restaurant," extra Reyna, an aspiring singer. "I desire to wake up loving what I am accomplishing."

"That's why I not long ago quit my career," laughed Fred.

In component, that is the appeal of Washington Heights. It follows a group of optimistic youthful folks because they aspire for some thing better than their conditions ?a no alcohol-induced fights, sloppy hook-ups or smush rooms needed. From the Heights, these youngsters struggle with serious issues. Jimmy almost ended his promising baseball job marketing medicines right after his father was sent to prison; Ludwin feels suffocated by his girlfriend's insecurities; and J.P. see's his mother's money struggles first-hand.

Meanwhile, MTV's other midseason reality series Buckwild ¡§C which follows a group of wild mates in West Virginia ¡§C is extra with the very same from your network that turned GTL right into a home title. Some could possibly wonder when the artistic renaissance represented in Washington Heights could also cause a cultural shift for MTV; one particular could only hope.

"You're likely to truly feel like you are viewing good friends," explained J.P. "You're not likely to truly feel like you are viewing these men and women you can not determine with. You will not be like, 'Who the hell are these individuals?'"

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CNN's 2013 travel want checklist

We've all got them: spots that reside big in imagination or memory, begging us to hop on the plane to uncover their delightful mysteries.

Because the new year kicks off, a handful of our incredibly well-traveled CNN correspondents -- who've been locations and noticed issues a lot of of us could under no circumstances see firsthand -- share their location wishes for 2013 and past.

Exactly where are you currently dreaming of going to this year? Please share your picks during the comments beneath. eight travel resolutions for 2013

Mongolia

Senior Global Correspondent Ben Wedeman set his sights on Mongolia early in daily life. "Back when I was, I believe, 9 or 10 many years old I go through a guide about Marco Polo, how he traveled with his uncles for the ultimate small business excursion for the Mongol Empire at its height," wrote Wedeman, who lately moved to Rome following an assignment in Cairo.

"The excursion lasted practically a quarter of the century, throughout which he grew up, mastered Mongolian, gained the self-confidence in the Mongol emperor, Kublai Khan, then inevitably returned household with wonderful tales of odd lands and stranger people today. The story hooked me."

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Wedeman socked away dollars from his initially career delivering newspapers with an eye toward a $3,000 excursion to Mongolia advertised from the Sunday New York Instances magazine. "Making close to $30 a month, it might have taken me over eight many years to come up using the revenue."

He study about Mongolia from the meantime but spent almost all of his teenage many years during the Arab globe, wherever he discovered the language and became keen on journalism, "for far better or for worse, a busier profession from the Middle East than in Mongolia, such as."

Wedeman took programs in classical and contemporary Mongolian though learning for his master's degree and located it "beastly hard."

He nonetheless needs to take a look at, during the spring or summer time, he mentioned. "Mongolian winters, when temperatures drop to ?30 ??C (?22 ??F) are usually not for me, thank you incredibly significantly."

He says he would employ a manual and horses and set out for that huge steppes.

"I know it is altered radically considering that I initial latched on towards the thought. For something it really is no longer a part of the communist bloc, it really is no longer isolated, and its economic climate is increasing quickly fueled by a mining boom (that's destroying the standard nomadic way of life, and severely harming the the moment pristine natural environment)."

The selling price now with an upscale organization is acceptable, he explained, "compared towards the $3,000 it had been back in 1971."

"Today precisely the same excursion is about $5000, which even though a nonetheless hefty sum, is, regarding inflation, a steal."

Jordan

CNN Senior Global Correspondent Nic Robertson spent considerably of your previous year in conflict-ridden areas that numerous travelers prevent today, together with Syria, Libya, Egypt and Lebanon. Up coming year, Robertson expects to travel to Afghanistan, Libya, Syria, Jordan and Mali in North Africa, exactly where he says al Qaeda is placing down roots.

So you'd imagine he could possibly want to shell out a while on the secluded seashore someplace. Nope. He desires to travel with his wife and two daughters (ages 17 and 21) to Jordan.

"I have however to consider my kids there and it's a quite particular spot to my wife and I as we met there while in the make as much as the primary Gulf War," wrote Robertson, briefly at your home in London, in an e-mail. "The hotel we met in, which was the CNN hotel, in the time identified as the Philadelphia, now the Radisson, was attacked by Zarqawi suicide bombers in 2005.

"Jordan nowadays is turning out to be significantly less steady and I'd want to consider my youngsters there to stop by spots like Petra, the Roman ruins in Amman and Jerash, the Dead Sea and Aqaba exactly where I discovered to dive. My eldest daughter's 2nd title is Jordan following the nation ... which means you can see the connection runs deep."

Galapagos Islands, Ecuador

Function has taken CNN Chief Political Correspondent Candy Crowley across the world, but in her absolutely free time she's "never been significantly of the traveler" past a yearly pilgrimage to Sleeping Bear Bay in Michigan, which Crowley calls "the area of my heart."

Still several many years ago, she was within a boat off the coast of Australia with her grown kids, residing out a travel dream.

"I started to determine substantial locations of dark brown spread across the horizon of blue water. I commenced to cry. I never ever believed a dream I had considering the fact that I was a teenager would come correct, but there I was about to scuba dive and snorkel in an spot of your Fantastic Barrier Reef," wrote Crowley.

"I really like water, sea daily life, scuba diving and snorkeling. I adore the warmth of sand just prior to it will get so hot you may need footwear. I adore a spot with that spiritual truly feel of historical past and mystery. I enjoy staying with my kids there to share."

Crowley's got her up coming fantasy excursion mapped out.

"Now I've a financial institution account with 'The Galapagos' written on it. It can be not while in the cards for 2013, but I will get there.

"I would like to do one among these week extended boat trips together with the scientists on board who inform you what you have witnessed, what you are about to determine simply because I believe it can ratchet up the awe element, if that is probable."

Pantanal area, Brazil

Shasta Darlington, a CNN correspondent primarily based in S?o Paulo, is established to check out the Pantanal area of Brazil.

"This is my 2nd time residing in Brazil and it is anything I failed to complete the initial time, so I would like to ensure I get there this time," wrote Darlington.

"It's the biggest contiguous wetland within the globe and teeming with animal lifestyle. The majority of people believe the Amazon could be the spot to head to see Brazilian flora and fauna, however the Pantanal area is effortlessly just as wealthy in animals and they are a lot easier to spot, specifically throughout rainy season when rivers rise forcing animals actually onto islands."

The area is tough to attain and navigate, Darlington explained, with generally lodge-like accommodations and boats, little planes and four-wheel-drive automobiles for transportation. However the rewards are wealthy. "There are an abundance of birds, monkeys, caimans, snakes, butterflies and fish around."

South Africa

"There are some locations that you just know the moment you phase off the plane will adjust you. For me, it truly is usually been Africa," wrote Patrick Oppmann, CNN's correspondent in Havana. He has visited the continent 3 times but has still to produce it to South Africa. "As a journalist, I've lengthy been fascinated with how South Africa is emerging from decades from the racial divisions from the Apartheid era.

"But it can be something to go through about individuals many years and an additional to basically take a look at Robben Island, in which Nelson Mandela was imprisoned, or to stroll in District six, the region in which a large number of black residents had their neighborhoods destroyed."

And obviously, the country's magnificent elegance can be a significant draw. "You can hit the seashore, hike Table Mountain overlooking Cape Town, consider in wonderful wildlife and cage dive amongst Excellent White sharks."

Oppmann would not miss attempting braai, the South African method of spit-roasting meat more than an open fire.

"And if there was a cold glass on the fantastic nearby wine or beer to go together with the braai, that will be just fine as well."

Exactly where are you currently dreaming about going in 2013?

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